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Authors
Peters, Anthony E.
Nguyen, Maggie
Green, Jennifer B.
Pearson, Ewan R
Buse, John B.
Sourij, Harald
Hernandez, Adrian F.
Sattar, Naveed
Holman, Rury R.
Mentz, Robert J.
Shah, Svati H.
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Funding
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (T32HL069749)
EXSCEL was sponsored and funded by Amylin Pharmaceuticals, Inc., a wholly owned subsidiary of AstraZeneca.
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Article History
Received: 4 February 2025
Accepted: 30 July 2025
First Online: 18 August 2025
Declarations
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: A.E.P has been supported by the National Heart Lung and Blood Institute (T32HL069749) and has received honoraria from Cytokinetics. J.B.G. receives research support from Merck, Roche and Boehringer Ingelheim/Lilly; honoraria for consulting from Boehringer Ingelheim/Lilly, Novo Nordisk, AstraZeneca, Pfizer, Sanofi, Bayer, Anji, Valo, Vertex, Merck. J.B.B. reports research support from Corcept, Dexcom, and Novo Nordisk; consulting fees from Altimmune, Amgen, ApStem, Aqua Medical, AstraZeneca, Boehringer-Ingelheim, CeQur, Corcept Therapeutics, Dexcom, Eli Lilly, embecta, GentiBio, Glyscend, Insulet, Medtronic MiniMed, Mellitus Health, Metsera, Novo Nordisk, Pendulum Therapeutics, Praetego, Stability Health, Tandem, Terns Inc, Vertex, Zealand; stock options from Glyscend, Mellitus Health, Pendulum Therapeutics, Praetego, and Stability Health. H.S. receives research support (to the Medical University of Graz) from Boehringer Ingelheim, Eli Lilly, Novo Nordisk and Sanofi and honoraria from AstraZeneca, Amarin, Bayer, Boehringer Ingelheim, Daiichy Sankyo, Eli Lilly, Novo Nordisk and Sanofi. R.R.H. reports personal fees from AstraZeneca, Lilly and Novartis. R.J.M. has received research support and honoraria from Abbott, American Regent, Amgen, AstraZeneca, Bayer, Boehringer Ingelheim/Eli Lilly, Boston Scientific, Cytokinetics, Fast BioMedical, Gilead, Innolife, Medtronic, Merck, Novartis, Relypsa, Respicardia, Roche, Sanofi, Vifor, Windtree Therapeutics, and Zoll. S.H.S. receives research support through sponsored research agreements with Lilly Inc., Verily Inc., AstraZeneca Inc. and nference. all other authors have no competing interests.
