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Single-Cell transcriptomic profiles of peripheral blood immune cells reveal early monocyte and platelet activation in the transition from high-risk states to clinical sepsis

Crossref DOI link: https://doi.org/10.1038/s41598-025-17078-y

Published Online: 2025-09-25

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sun, Lanlan

Zhang, Peng

Zhang, Haikun

Fan, Hailang

Li, Yansheng

Zhao, Yaqian

Wang, Mengtong

Huang, Yingdi

Liu, Mingyang

Zhang, Dake

Zhang, Xin
Funding

Funding for this research was provided by:

Higher Education Discipline Innovation Project (111 Project No. B13003)

Beijing Nova Program (NO.20240484538)
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Text and Data Mining valid from 2025-09-25

Version of Record valid from 2025-09-25
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Article History

Received: 6 June 2025

Accepted: 20 August 2025

First Online: 25 September 2025

Declarations

:

: The authors declare no competing interests.

: This study was approved by the Ethics Committee of Beijing Chaoyang Hospital of Capital Medical University (2023-KE-352). Informed written consent were obtained prior to the procedure.

: All the authors agree for the publication.

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