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Concentrations of ciprofloxacin in food defined as safe alter the gut microbiome and ciprofloxacin susceptibility in humans: an interventional clinical study

Crossref DOI link: https://doi.org/10.1038/s41598-025-18714-3

Published Online: 2025-10-07

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Manoharan-Basil, Sheeba

Gestels, Zina

Abdellati, Said

Vanbaelen, Thibaut

Van Den Bossche, Dorien

van Alebeek, Lajoy

Van Herrewege, Yven

Poppe, Lindsay

Vandenhove, Leen

Bracke, Stefanie

Smekens, Bart

Jacobs, Bart

Genbrugge, Els

Kenyon, Chris
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Text and Data Mining valid from 2025-10-07

Version of Record valid from 2025-10-07
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Article History

Received: 5 May 2025

Accepted: 3 September 2025

First Online: 7 October 2025

Declarations

:

: The authors declare no competing interests.

: All participants provided written informed consent at baseline (visit 1). The Institutional Review Board of the ITM, the designated Belgian EC, and the Competent Authorities of Belgium (FAMPH) approved the trial. The study was registered in the EU Clinical Trials Register (EU CT number 2023-506205-18-00; ; Trial registration 23/02/2024).

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