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Article History

Received: 14 June 2025

Accepted: 3 September 2025

First Online: 6 October 2025

Declarations

:

: The authors declare no competing interests.

: This study was approved by the Ethics Committee of Beijing Jishuitan Hospital, Capital Medical University (Ethics Approval No. [K2025] NO. [018]-00). All participants provided written informed consent prior to sample collection, in accordance with the Declaration of Helsinki and institutional guidelines. All methods were performed in accordance with the relevant guidelines and regulations.

: All participants were informed of the study’s purpose and agreed to the publication of clinical data and research findings. No identifiable patient information is included in the manuscript.