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Nasal immunization with Streptococcus mutans membrane vesicles and eggshell-derived hydroxyapatites elicits enhanced antigen-specific mucosal IgA responses

Crossref DOI link: https://doi.org/10.1038/s41598-025-19334-7

Published Online: 2025-10-15

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hashizume-Takizawa, Tomomi

Mochizuki, Chihiro

Sakai, Yuki

Nakamura, Koichi

Kobayashi, Hirotaka

Senpuku, Hidenobu
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (JP22K09950, JP20K10286)

BIOAPATITE, INC

Nihon University Research Grant
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Text and Data Mining valid from 2025-10-15

Version of Record valid from 2025-10-15
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Article History

Received: 6 June 2025

Accepted: 8 September 2025

First Online: 15 October 2025

Declarations

:

: This work was supported by a funding from BIOAPATITE, INC. to which the authors belong.

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