Hoshino, Masaki
Yasui, Yukari
Mitsumata, Shun
Ito, Yuko
Kawauchi, Hiroki
Komatsu, Ryuichi
Kimbara, Atsushi
Horiba, Naoshi
Article History
Received: 9 June 2025
Accepted: 15 September 2025
First Online: 17 October 2025
Declarations
:
: Atsushi Kimbara is an inventor on a patent application (WO2023-JP211) related to the compound CH7450924 described in this study. All authors are employees of Chugai Pharmaceutical Co., Ltd.
: Animal procedures and protocols were in accordance with the Guidelines for the Care and Use of Laboratory Animals at Chugai Pharmaceutical Co. Ltd. and approved by the Institutional Animal Care and Use Committee (approval No.21–174, 23–145, 24–164, 24–182, 24–186, 24–284) and were also compliance with the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines.