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Authors
Jekell, Andreas
Ekholm, Mikael
Kahan, Thomas
Lundwall, Kristina
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Funding
Funding for this research was provided by:
Karolinska Institute
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Article History
Received: 12 April 2025
Accepted: 21 October 2025
First Online: 28 October 2025
Declarations
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: KL is currently employed by Boehringer Ingelheim; this employment commenced after the completion of the study. All the authors declare no competing interest.
: Both studies were approved of by the Regional Ethical Review Board in Stockholm (DoRa: #03-728, 210/750 − 32; SOLID #2009/1706-31/2, 2019–04876) and were performed in accordance with guidelines and regulations by the Regional Ethical Review Board, and in accordance with the Declaration of Helsinki. Oral and written informed consent was obtained from all study participants. The DoRa and SOLID studies are registered at ClinicalTrials.gov (NCT02901977 and NCT01204528).
