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Comparing alignment and de-novo approaches for gut microbiota metagenomic data analysis reveals differences in taxonomic resolution and novel functional insights

Crossref DOI link: https://doi.org/10.1038/s41598-025-26617-6

Published Online: 2025-11-27

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kuzmichenko, Polina

Fedorov, Dmitry

Galeeva, Julia

Postoeva, Anna

Krieger, Ekaterina

Kudryavtsev, Alexander

Pavlenko, Alexander

Vvedensky, Andrey

Starikova, Elizaveta

Govorun, Vadim

Ilina, Elena
Funding

Funding for this research was provided by:

Wellcome Trust Strategic Award (100217)

Ministry of Science and Higher Education of the Russian Federation (075-15-2025-530)
License Information

Text and Data Mining valid from 2025-11-27

Version of Record valid from 2025-11-27
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Article History

Received: 28 July 2025

Accepted: 29 October 2025

First Online: 27 November 2025

Declarations

:

: The authors declare no competing interests.

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