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Comparing deep learning CNN method with traditional MRI-based hippocampal segmentation and volumetry for early Alzheimer’s disease diagnosis across diverse populations

Crossref DOI link: https://doi.org/10.1038/s41598-025-29366-8

Published Online: 2025-12-02

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ibrahim, Nur Shahidatul Nabila

Suppiah, Subapriya

Ibrahim, Buhari

Mohad Azmi, Nur Hafizah

Seriramulu, Vengkatha Priya

Mohamad, Mazlyfarina

Hanafi, Marsyita

Mohammad Sallehuddin, Hakimah

Omar Sharif, Nurallysha Najwa

Razali, Rizah Mazzuin

Harrun, Noor Harzana
Funding

Funding for this research was provided by:

Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK03/UPM/02/4)

Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK03/UPM/02/4)

Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK03/UPM/02/4)

Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK03/UPM/02/4)

Ministry of Higher Education, Malaysia (FRGS/1/2019/SKK03/UPM/02/4)
License Information

Text and Data Mining valid from 2025-12-02

Version of Record valid from 2026-01-03
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Article History

Received: 31 May 2025

Accepted: 17 November 2025

First Online: 2 December 2025

Declarations

:

: The authors declare no competing interests.

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