Hao, Fengxiang
Qin, Danlei
Li, Ran
Li, Xia
Hou, Jiayi
Zhao, Bin
Funding for this research was provided by:
the overseas students selected Foundation of Shanxi Province science (No. 20220020)
the National Natural Science Foundation Youth Science Fund project of china (Nos. 82202622)
the Shanxi Key R&D Planning Program (202202130501009)
Article History
Received: 7 May 2025
Accepted: 21 November 2025
First Online: 29 November 2025
Competing interests
: The authors declare no competing interests.
: All experimental animals were housed in a specific pathogen-free (SPF) facility under standardized environmental conditions (temperature 22 ± 2 °C, humidity 50 ± 10%, 12-h light–dark cycle). All procedures strictly adhered to institutional and national laboratory animal management regulations (Regulations on the Management of Laboratory Animals in China). Anesthesia induction and maintenance were performed using 2% isoflurane, and euthanasia was carried out via cervical dislocation once deep anesthesia was achieved. All animal experiments were conducted in accordance with the ARRIVE guidelines and the NIH Guide for the Care and Use of Laboratory Animals. All procedures were approved by the Animal Experiment Ethics Committee of Shanxi University of Chinese Medicine (Approval No. 2023KY-07013).