Ruiz, Pablo https://orcid.org/0000-0002-5810-8802
Millán, Olga https://orcid.org/0000-0002-6861-5832
Fundora, Yiliam https://orcid.org/0000-0003-4950-6988
Julian, Judit https://orcid.org/0009-0008-7137-9210
Crespo, Gonzalo https://orcid.org/0000-0002-1178-4897
Bataller, Ramón https://orcid.org/0000-0002-1119-7799
Colmenero, Jordi https://orcid.org/0000-0001-6024-8479
Brunet, Mercè https://orcid.org/0000-0002-7154-916X
Funding for this research was provided by:
Instituto de Salud Carlos III (PI19/00378)
Instituto de Salud Carlos III (PI19/00378)
Article History
Received: 2 September 2025
Accepted: 8 December 2025
First Online: 20 December 2025
Declarations
:
: All the authors declare that they have no competing interests.
: This study was performed in accordance with the Declaration of Helsinki and the E6 Good Clinical Practice Standards ICH and fulfilled the criteria established by the Organic Law of Biomedical Research 14/2007 and the Organic Law of Protection of Personal Data 3/2018. The study was approved by the local Clinical Research Ethics Committee (approval number HCB/2019/0258). All patients were informed about the study and provided written informed consent for inclusion.