He, Siheng
Liu, Lixin
Chen, Lu
Fan, Huabin
Shao, Feng
Sun, Shudan
Zhang, Xiaowen
Hu, Sheng
Funding for this research was provided by:
Yunnan Provincial Ten Thousand Talents Program for Distinguished Physicians (YNWR-MY-2018-073)
Yunnan Science Technology Programme (202101AC070079)
Scientific Research Fund of Yunnan Provincial Department of Education (2024J0242)
the Scientific Research Project of Yunnan Provincial Clinical Medical Center (20241224135402)
the Joint Special Project of Yunnan Provincial Science and Technology Department and Kunming Medical University (202501AY070001-100)
Applied Basic Research Joint special Fund project of Science and Technology Department of Yunan Province and Kunming Medical University (202201AY070001-102)
the Doctoral Research Project of the Second Affiliated Hospital of Kunming Medical University (2023BS03)
the National Natural Science Foundation of China (81760430)
Article History
Received: 22 June 2025
Accepted: 12 December 2025
First Online: 20 December 2025
Declarations
:
: The authors declare no competing interests.
: RT-qPCR analyses were performed on fresh-frozen human tissue specimens (not archival material). All included samples were obtained after written informed consent from the patients. The study protocol was reviewed and approved by the institutional ethics committee (approval No. kyfeyxm2024013), and all procedures were conducted in accordance with medical research ethics guidelines, including the Declaration of Helsinki.