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In-silico studies, synthesis, and pharmacological screening of novel multitarget diphenylpyrazole scaffold as EGFR/BRAF and cyclooxygenase-2 inhibitors

Crossref DOI link: https://doi.org/10.1038/s41598-025-33006-6

Published Online: 2025-12-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Abdelgawad, Mohamed A.

Bukhari, Syed N. A.

Elkomy, Mohammed H.

Elmowafy, Mohammed

Mostafa, Ehab M.

Musa, Arafa

Ahmad, Waqas

Abdel-Bakky, Mohamed Sadek

Farouk, Amr

Elshemy, Heba A. H.

El-Din, Asmaa G. Safi
Funding

Funding for this research was provided by:

the Deanship of Graduate Studies and Scientific Research at Jouf University (DGSSR-2025-FC-01022)
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Text and Data Mining valid from 2025-12-23

Version of Record valid from 2026-01-15
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Article History

Received: 11 October 2025

Accepted: 15 December 2025

First Online: 23 December 2025

Declarations

:

: The authors declare no competing interests.

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