Zhang, Ling
Liu, Yi
Liu, Ruiqi
Wang, Wenjun
Li, Ruiji
Funding for this research was provided by:
Natural Science Foundation of Shandong Province (ZR2021QH294)
Natural Science Foundation of Shandong Province (ZR2021QB124)
Research Fund for Academician Lin He New Medicine (JYHL2022MS02)
Outstanding Youth Foundation (Overseas) Project of Rizhao City Natural Science Foundation (RZ2021ZR1)
Article History
Received: 7 October 2025
Accepted: 22 December 2025
First Online: 26 December 2025
Declarations
:
: The authors declare no competing interests.
: This study involving CRC patients and node mice were approved by the Medical Research Ethics Committee of the Affiliated Hospital of Jining Medical University (No. 2021B052). And this study was performed in line with the principles of the Declaration of Helsinki and the ARRIVE guidelines. Informed consent was obtained from all individual participants included in the study.