Zhu, Jialiang
Zhang, Ruiheng
Zhang, Chen
Yan, Yali
Guo, Yajing
Tian, Gang
Wang, Jinming
Liu, Min
Hao, Yibin
Funding for this research was provided by:
Creation and Application of an Intelligent “Four Highs” Early Warning and Prevention Model (251111312800)
Multi-omics Pathogenesis and Prospective Intervention Cohort Study on Hypertension in Children and Adolescents in Henan Province (231111313400)
Research and Application of Large Model-Driven Hypertension Pathogenesis, Screening Models, and Intervention Paradigms (SBGJ202401001)
Construction and Application of an Intelligent Prevention and Treatment System for Hypertension in Children and Adolescents in the Central Plains Region (HNCRD202402)
Article History
Received: 4 September 2025
Accepted: 24 December 2025
First Online: 6 January 2026
Declarations
:
: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
: This study involves human participants, has obtained ethical approval, and all participants have provided consent to participate. This study provided a revised informed consent form (V2.0/2022.07.10) to all participating children and adolescents and their guardians, and each participant and their guardian signed the informed consent form and voluntarily participated in this study. The ethical approval of this study was undertaken by the Medical Ethics Committee of Henan Provincial Center for Disease Control and Prevention, with the approval number 2022-KY-006-02.