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Authors
Gao, Yuanjing
Gu, Difei
Li, Juan
Niu, Zihan
Liu, Rui
Luo, Yanwen
Zhou, Mengyuan
Xiao, Mengsu
Mao, Feng
Zhou, Yidong
Jiang, Yuxin
Li, Hongsheng
Lu, Man
Zhu, Qingli
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Funding
Funding for this research was provided by:
National Natural Sciences Foundation of China (82171967)
National High-Level Hospital Clinical Research Funding (No. 2022-PUMCH-B-065)
CAMS Clinical and translational medicine research specialty (2024-I2M-C&T-B-035)
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Article History
Received: 29 October 2025
Accepted: 28 December 2025
First Online: 4 January 2026
Competing interests
: The authors declare no competing interests.
: This study was a prospective multicenter study and was approved by the Ethics Committee of Peking Union Medical College Hospital (approval number: ZA-2291). This study was conducted in accordance with the 1964 Helsinki Declaration and its later amendments. This study was registered at with the clinical trial registration number ChiCTR2000031231 on March 25, 2020. Written informed consent was obtained from all individual participants included in the study.
