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In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in β-thalassemia

Crossref DOI link: https://doi.org/10.1038/s41598-025-94222-8

Published Online: 2025-03-15

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Deleuze, Virginie

Stephen, Tharshana

Salma, Mohammad

Orfeo, Cédric

Jorna, Ruud

Maas, Alex

Barroca, Vilma

Arcangeli, Marie-Laure

Lecellier, Charles-Henri

Andrieu-Soler, Charlotte

Grosveld, Frank

Soler, Eric
Funding

Funding for this research was provided by:

Labex GR-Ex (ANR-11-LABX-0051, ANR-11-LABX-0051, ANR-11-LABX-0051)

SIRIC Montpellier Cancer (INCa-DGOS-INSERM- ITMO Cancer_ 18004, INCa-DGOS-INSERM- ITMO Cancer_ 18004)

Labex EpiGenMed (ANR-10-LABX-12-01)

Fondation pour la Recherche Médicale (FRM DEQ20180339221)
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Text and Data Mining valid from 2025-03-15

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Article History

Received: 13 January 2025

Accepted: 12 March 2025

First Online: 15 March 2025

Declaration

:

: The authors declare no competing interests.

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