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Authors
Aranda-Díaz, Andrés
Neubauer Vickers, Eric
Murie, Kathryn
Palmer, Brian
Hathaway, Nicholas
Gerlovina, Inna
Boene, Simone
García-Ulloa, Manuel
Cisteró, Pau
Katairo, Thomas
Semakuba, Francis Ddumba
Nsengimaana, Bienvenu
Gwarinda, Hazel
García-Fernández, Carla
Louie, William
Esayas, Endashaw
Da Silva, Clemente
Datta, Debayan
Kiyaga, Shahiid
Wiringilimaana, Innocent
Feleke, Sindew Mekasha
Bennett, Adam
Smith, Jennifer L.
Gadisa, Endalamaw
Parr, Jonathan B.
Conrad, Melissa D.
Raman, Jaishree
Tukwasibwe, Stephen
Ssewanyana, Isaac
Rovira-Vallbona, Eduard
Tato, Cristina M.
Briggs, Jessica
Mayor, Alfredo
Greenhouse, Bryan
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Funding
Funding for this research was provided by:
Bill and Melinda Gates Foundation (INV-003212, INV-024346, INV-003212, OPP1209843, INV-031512, INV-037316, INV-019032, OPP1132226)
National Institute of Allergy and Infectious Diseases (5K01AI153555, R01 AI77791, K23AI166009, K24AI144048)
Global Fund (EPHI5405)
Generalitat de Catalunya (CEX2023-0001290-S)
Departament d’Universitats i Recerca, Generalitat de Catalunya (2017 SGR 664)
Ministerio de Ciencia e Innovación (PID2020-118328RB-I00/AEI/10.13039/501100011033)
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Article History
Received: 25 September 2024
Accepted: 17 March 2025
First Online: 28 March 2025
Declarations
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: J.B.P. reports research support from Gilead Sciences, non-financial support from Abbott Laboratories, and consulting for Zymeron Corporation, all outside the scope of the current work. All other authors report no potential conflicts of interest.
: Ethical approval for the study that generated the 26 field samples from Ethiopia3 was granted by the Ethiopia Public Health Institute (EPHI) Institutional Review Board (IRB; protocol EPHI-IRB-033-2017) and WHO Research Ethics Review Committee (protocol ERC.0003174 001). Processing of de-identified samples and data at the University of North Carolina at Chapel Hill (UNC) was determined to constitute non-human subjects research by the UNC IRB (study 17–0155). The study was determined to be non-research by the Centers for Disease Control (CDC) and Prevention Human Subjects office (0900f3eb81bb60b9). Study protocols for the study that generated the data for the 436 field samples from Mozambique22 were approved by the ethical committees of CISM and Hospital Clínic of Barcelona, and the Mozambican Ministry of Health National Bioethics Committee. Ethical approval for the studies that included the collection of blood samples used in mosquito feeding assays was received from the Uganda Council of Science and Technology, Makerere University School of Medicine, the University of California, and the London School of Hygiene & Tropical Medicine. Ethical approval for the study that collected P. falciparum and P. vivax samples in Northern Ethiopia in 2022–2023 was obtained from the National Research Ethical Review Committee, Addis Ababa, Ethiopia (reference number: 02/256/630/14), AHRI/ALERT Ethics Review Committee (protocol number: P0-08-22), Aklilu Lemma Institute of Pathobiology Institutional Research Ethics Review Committee (reference number: ALIPB IRERC/111/2015/23) and the WCG IRB approval (protocol number: 1769134-1; IRB tracking number: 20214694). Participants, or guardians/parents in the case of minors, in all these studies provided written informed consent. All research was performed in accordance with relevant guidelines and regulations.
