Shahbad, Ramin
Kazim, Madihah
Razian, Sayed Ahmadreza
Desyatova, Anastasia
Jadidi, Majid
Funding for this research was provided by:
National Heart, Lung, and Blood Institute (R01HL147128)
National Institute of General Medical Sciences (P20GM152301)
National Institute of General Medical Sciences (P20GM152301)
Nebraska Tobacco Settlement Biomedical Research Development Fund
Article History
Received: 11 December 2024
Accepted: 18 March 2025
First Online: 1 April 2025
Competing interests
: The authors declare no competing interests.
: The human aortic tissues used in this study were obtained from deceased donors through an organ procurement organization (Live On Nebraska) with informed consent provided by the next of kin. The collection and use of these tissues adhered to all relevant guidelines and regulations, including the Declaration of Helsinki. According to the U.S. Department of Health and Human Services and institutional guidelines, research involving cadaveric tissues does not constitute research on human subjects and, therefore, does not require Institutional Review Board (IRB) approval. Ethical approval was waived due to the nature of the study. All experiments were conducted in accordance with IBC protocol #20-10-045-BL2, which was approved by the University of Nebraska at Omaha Environmental Health and Safety Office.