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Authors
de Vasconcellos, Jaira Ferreira
Westbrook, Phillip
Dingle, Marvin
Dimtchev, Alexander
Raiciulescu, Sorana
Schellhase, Christopher W.
Piscoya, Andres
Putko, Robert
Bedrin, Michael
Cole, Hisae
Cubbage, Nicole
Dargan, Lauren Jeannette
Pellegrini, Vincent D. Jr.
Nesti, Leon J.
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Funding
Funding for this research was provided by:
USAMRAA BAA (W81XWH-17-2-0009, W81XWH-17-2-0009)
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Article History
Received: 16 April 2024
Accepted: 1 April 2025
First Online: 24 April 2025
Declarations
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: The authors declare no competing interests.
: Primary MPCs were harvested from debrided traumatized human muscle tissue from injured service members during their initial surgical debridement at Walter Reed National Military Medical Center. Tissue specimens used in this study were taken at the margin of devitalized and healthy-appearing tissue that would otherwise be discarded as surgical waste. The Walter Reed National Military Medical Center Institutional Review Board approved this tissue procurement protocol and the need to obtain informed consent was waived by the Walter Reed National Military Medical Center Institutional Review Board. All experimental protocols were performed in accordance with relevant guidelines and regulations.
: All animal procedures were approved by the Institutional Animal Care and Use Committee at the Medical University of South Carolina. Animal experiments were performed in compliance with the “Animal Research: Reporting of In Vivo Experiments” (ARRIVE) guidelines (). All animal experiments were performed in accordance with relevant guidelines and regulations.
