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In Silico and in vitro evaluation of the anticancer effect of a 1,5-Benzodiazepin-2-One derivative (3b) revealing potent dual inhibition of HER2 and HDAC1

Crossref DOI link: https://doi.org/10.1038/s41598-025-97786-7

Published Online: 2025-04-18

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Al-Theyab, Nada S.

Bakheit, Ahmad H.

Lahmidi, Sanae

Alanazi, Mohammed Mufadhe

Ali, Awadh M

Azzaoui, Khalil

Essassi, El Mokhtar

Mague, Joel T.

Hefnawy, Mohamad

Alanazi, Mohammed Mater

Alanazi, Ashwag S.
Funding

Funding for this research was provided by:

Deanship of Scientific Research, King Saud University (RSPD2025R754, RSPD2025R754, RSPD2025R754, RSPD2025R754, RSPD2025R754, RSPD2025R754)

Princess Nourah Bint Abdulrahman University (PNURSP2025R342)
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Text and Data Mining valid from 2025-04-18

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Article History

Received: 10 January 2025

Accepted: 7 April 2025

First Online: 18 April 2025

Declarations

:

: The authors declare no competing interests.

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