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Authors
Põld, Ave
Toompere, Karolin
Elken, Aet
Viigimaa, Margus
Irs, Alar
Nohrin, Lembi Caroline
Fischer, Krista
Milani, Lili
Alavere, Helene
Alloja, Janika
Pärna, Kersti
Traks, Tanel
Kalda, Ruth
Widen, Elisabeth
Ripatti, Samuli
Jürisson, Mikk
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Funding
Funding for this research was provided by:
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Horizon 2020 Framework Programme (101016775)
Eesti Teadusagentuur (PRG2078)
Eesti Teadusagentuur (PRG2629)
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Article History
Received: 8 October 2025
Accepted: 1 January 2026
First Online: 9 January 2026
Declarations
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: The authors declare no competing interests.
: All procedures performed in studies involving human participants were in accordance with the principles of the Declaration of Helsinki 76 . Participation in the clinical trial was voluntary, informed consent was obtained from all individual participants included in the study. Ethical approval was granted by the Estonian Bioethics and Human Research Council (No. 1.1–12/1726, 17.08.2021), the trial registration number on ClinicalTrials.gov: NCT05603663.
: Not applicable, as this trial does not include any details, images, or videos relating to individual participants.
