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Alkaloids from Evodia rutaecarpa inhibit the occurrence and development of gallbladder cancer in vivo and in vitro

Crossref DOI link: https://doi.org/10.1038/s41598-026-35563-w

Published Online: 2026-03-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Yijie

Zhou, Shufen

Xu, Hanzheng

Zhou, Hongye

Sun, Kunqi

Hu, Siyang

Xu, Ke

Yang, Jiahua

Chen, Yafeng

Li, Wei
Funding

Funding for this research was provided by:

Fujian Provincial Natural Science Foundation of China (No. 2024J01222)

the National Key Research and Development Program of China (No. 2024YFA1108604)

Science and Technology Innovation Project of Shanghai Putuo District Health and Wellness Plan (No. ptkwws202308)

Shanghai Health System Key Disciplines - General Surgery (No. 2024ZDXK0046)

the Clinical Specialized Disease Construction Project of Shanghai Putuo District Municipal Health Commission (No.2024tszb01)
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Text and Data Mining valid from 2026-03-13

Accepted Manuscript valid from 2026-03-13
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Article History

Received: 5 June 2025

Accepted: 7 January 2026

First Online: 13 March 2026

Declarations

:

: The authors declare no competing interests.

: This study adhered strictly to the ARRIVE guidelines in its design and reporting to ensure animal welfare and research transparency. All experiments were conducted in compliance with the ethical review requirements of [the Institutional Animal Care and Use Committee of Putuo Hospital, Shanghai University of Traditional Chinese Medicine, China] (Ethics Approval Number: DWEC-A-2023-01-1–69), and efforts were made to minimize the number of animals used and their suffering.This study did not involve human participants, human experimentation, or the use of human tissue samples. Therefore, no institutional review board or ethics committee approval was required or sought.

: All authors agree to submit the article for publication.

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