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Authors
Laczó, Martina
Maleninska, Kristyna
Khazaalova, Natalie
Borovska, Sarka
Vyhnalek, Martin
Hort, Jakub
Stuchlik, Ales
Svoboda, Jan
Laczó, Jan
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Funding
Funding for this research was provided by:
Grant Agency of Charles University (40125)
Alzheimer’s Foundation
Martina Roeselová Memorial Fellowship
Czech Science Foundation (22-33968S)
Czech Science Foundation (21-16667K)
National Institute for Neurological Research (LX22NPO5107)
Ministry of Health of the Czech Republic — conceptual development of research organization, University Hospital Motol, Prague, Czech Republic grant (00064203)
Institutional Support of Excellence 3 2. LF UK (6980382)
Ministry of Health of the Czech Republic (NW25-04-00337)
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Article History
Received: 11 October 2025
Accepted: 12 January 2026
First Online: 22 January 2026
Declarations
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: JH is a medical advisor at Neurona lab, Terrapino mobile app, consulted for Eisai, Eli Lilly, Biogen, Schwabe, and holds stock options in Alzheon. Other authors declare no competing interests.
: In the human study, all participants provided written informed consent, and the study was approved by the Ethics Committee of Motol University Hospital (consent number EK701/16). The study was performed in accordance with Alzheimer’s Association guidelines and the Declaration of Helsinki. In the animal study, the experimental and housing conditions were approved by the Resort Committee of Animal Welfare (51-2022-P) and complied with the European Community Council Directive (2010/63/EC).
