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Authors
Hu, Yanglin
Shi, Mingjun
Huang, Qian
Wan, Sheng
Zhang, Miao
Wang, Zengsi
Huang, Wei
Zhang, Shuang
Xiong, Fei
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Funding
Funding for this research was provided by:
The Funding for Scientific Research Projects from Wuhan Municipal Health Commission (WX23A49)
Knowledge Innovation Project of Wuhan Science and Technology Bureau (No. 2023020201010184)
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Article History
Received: 17 September 2025
Accepted: 13 January 2026
First Online: 17 January 2026
Declarations
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: The authors declare no competing interests.
: This study was conducted in strict accordance with the ethical principles of the Declaration of Helsinki and was approved by the Medical Ethics Committee of Wuhan No.1 Hospital (Approval No.: Kelun [2024]51). All patients with ANCA-associated vasculitis (AAV) and healthy volunteers provided written informed consent for participation and the use of their plasma samples for complement testing. Sample collection was performed following standard clinical and laboratory procedures, with all participant data anonymized to ensure privacy and data security.
