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Article History

Received: 25 June 2025

Accepted: 23 January 2026

First Online: 6 February 2026

Declarations

:

: The authors declare no competing interests.

: This research protocol was approved by the Ethics Committee of the Affiliated Hospital of Zunyi Medical University (Approval Number: KLL-2022-844), and strictly adhered to the “Measures for the Ethical Review of Biomedical Research Involving Human Subjects” and the “Declaration of Helsinki” .

: All patients/participants involved in the study signed a standardized written informed consent form provided by the Affiliated Hospital of Zunyi Medical University, which covered the purpose of the study, risks, and terms for anonymizing data.

: All mouse experiments were approved by the Laboratory Animal Ethics Committee of the Affiliated Hospital of Zunyi Medical University (Approval Number: zyfy-an-2023-0332), and the experimental procedures conformed to the “Regulations on the Management of Laboratory Animals” and the “Guiding Opinions on the Humane Treatment of Laboratory Animals” .