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Authors
Miguel-Batuecas, Andrea
De Pablo-Moreno, Juan A.
Porras, Néstor
Bermejo-Álvarez, Pablo
González-Brusi, Leopoldo
Serrano, Luis J.
De Pablo-Moreno, Javier M.
Sánchez, María José
García-Arranz, Mariano
Rodríguez-Bertos, Antonio
Chumappumkal Joseph, Bilgimol
Revuelta, Luis
Liras, Antonio
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Funding
Funding for this research was provided by:
Community of Madrid, Spain (CT85/23)
Complutense University of Madrid and Banco Santander (CT63/19-CT64/19)
Ministerio de Ciencia e Innovación (PID2020-117501RB-I00)
Regional Government of Andalusia, Department of Innovation (PAI-BIO-295)
Association for Research and Cure of Factor V deficiency (ASDEFAV/2021-25)
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Article History
Received: 9 September 2025
Accepted: 29 January 2026
First Online: 12 February 2026
Declarations
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: The authors declare that they have no competing interests. AL, JADPM, LR, AMB, PBA, and LGB, have a mouse model, deficient infactor V, protected by Spanish patent (Ref. ES2948817B2). Holders: Complutense University of Madrid, and Superior Council for Scientific Research. Spain. Official Bulletin of Industrial Property (21-02-2024) Volume 2: Inventions. p. 8. Available in: https://sede.oepm.gob.es/bopiweb/descargaPublicaciones/formBusqueda.action
: The study was conducted in compliance with Royal Decree 53/2013 and Directive 2010/63/EU. All procedures used were approved by the School of Veterinary Medicine of the Complutense University of Madrid, the Ethics Committees on Animal Experimentation of the Complutense University, and the Madrid Regional Government (PROEX 040/17 and PROEX 358.4/21).
