Smeenk, Hilde
Lendemeijer, Bas
Buurma, Mirle G.
Forgione, Michell A.
Slump, Denise E.
Monshouwer, Roos A.
Wallaard, Ilse
Mientjes, Edwin J.
Hoogendijk, Witte J. G.
Elgersma, Ype
de Vrij, Femke M. S.
Kushner, Steven A.
Funding for this research was provided by:
ZonMw (1025002211000)
ZonMw (452022211)
ZonMw (1025002211000)
ZonMw (1025002211000)
ZonMw (1025002211000)
ZonMw (1025002211000)
Ministry of Education, Culture and Science of the government of the Netherlands (024.003.001)
Ministry of Education, Culture and Science of the government of the Netherlands (024.003.001)
Article History
Received: 25 November 2025
Accepted: 18 February 2026
First Online: 28 February 2026
Declarations
:
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. In addition, all mouse experiments were conducted in accordance with ARRIVE guidelines and the European Commission Council Directive 2010/63/EU. We obtained national and local approval under CCD license AVD1010020173544 and AVD10100202215931 (Centrale Commissie Dierproeven, the Hague, the Netherlands).