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Authors
Lim, Rui Hen
Talker, Leeran
Broomfield, Henry
Dogan, Cihan
Selim, Ahmed B.
Lambert, Gabriel
Carter, Julian C.
Neville, Daniel M.
Wiffen, Laura
Brown, Thomas
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Winter, Jonathan
Gribbin, Andrew
Chauhan, Milan
De Vos, Ruth
Kalra, Paul
Begum, Selina
Vijaykumar, Elango
Chauhan, Anoop J.
Patel, Ameera X.
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Funding
Funding for this research was provided by:
Innovate UK (133879)
SBRI Healthcare
Pfizer OpenAir
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Article History
Received: 9 October 2025
Accepted: 23 February 2026
First Online: 26 February 2026
Declarations
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: RHL, LT, CD, HB, ABS, GL, JCC, AXP are currently employed, or were employed/funded at the time of the research, by TidalSense Limited. The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, SBRI, Pfizer, UKRI or the Department of Health and Social Care.
: All participants gave written informed consent to participate in the studies. Ethical approval was obtained from Yorkshire & The Humber - Bradford Leeds Research Ethics Committee (Reference 15/YH/0369) for CBRS, West Midlands - Solihull Research Ethics Committee (Reference 17/WM/0228) for CBRS2, and Yorkshire & The Humber - Bradford Leeds Research Ethics Committee (Reference 21/YH/0094) for CARES. Further details can be found on the National Library of Medicine’s Clinical Trial website for CBRS (NCT02814253), CBRS2 (NCT03615365), and CARES (NCT04939558).
