Tooming, Mikk
Toome, Kadri
Rekker, Kadri
Roht, Laura
Laidre, Piret
Fjodorova, Olga
Roomere, Hanno
Murumets, Ülle
Šamarina, Ustina
Pajusalu, Sander
Žordania, Riina
Tael, Kristi
Vaidla, Eve
Kurvinen, Elvira
Tõnisson, Neeme
Ilisson, Mihkel
Padrik, Peeter
Lehtsaar, Jaak
Kütner, Riina
Vettus, Elen
Vahar, Helen
Peets, Pilleriin
Õunap, Katrin
Kahre, Tiina
Funding for this research was provided by:
Estonian Research Competency Council (PSG774)
Estonian Research Competency Council (PSG1027)
Estonian Research Competency Council (PRG2040)
Article History
Received: 14 November 2025
Accepted: 4 March 2026
First Online: 13 March 2026
Declarations
:
: The authors declare no competing interests.
: All procedures involving human participants were conducted in accordance with institutional guidelines and the Declaration of Helsinki. Written informed consent for genetic testing and the use of anonymized clinical data for research purposes was obtained from all participants and/or their legal guardians. The manuscript does not include any images or information that could identify individual participants; therefore, specific consent for publication of identifying information was not required. The study was approved by the Research Ethics Committee of the University of Tartu (332/T 2, 21.12.2020; 341/M 2, 17.02.2021; 359/M 9, 21.02.2022; 384/M 14, 20.11.2023; 389/M 1, 15.04.2024).