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Deciphering the mechanisms underlying the dual-target inhibition of carbohydrate-digesting and neurodegenerative enzymes by Syzygium aromaticum (L.) Merr. & L.M. via molecular docking and dynamics simulations

Crossref DOI link: https://doi.org/10.1038/s41598-026-45482-5

Published Online: 2026-03-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ojo, Oluwafemi Adeleke

Gyebi, Gideon Ampoma

Iyobhebhe, Matthew

Dada, Samuel

Daramola, Tolulope

Ojo, Adebola Busola

Oyebamiji, Abel Kolawole

Oyinloye, Babatunji Emmanuel

Ajiboye, Basiru Olaitan
License Information

Text and Data Mining valid from 2026-03-23

Accepted Manuscript valid from 2026-03-23
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Article History

Received: 7 January 2026

Accepted: 19 March 2026

First Online: 23 March 2026

Declarations

:

: The authors declare no competing interests.

: The Institutional Research Animal Ethical Committee approved (BUI/BCH/2024/0002) the study protocols and research conducted in accordance with the ARRIVE (Animal Research: Reporting In Vivo Experiments) guidelines. All the experimental methods were performed in accordance with the relevant protocols, guidelines and regulations approved by the Bowen University Research Ethics Committee (BUREC).

: Not applicable.

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