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Authors
Jiang, Liping
Xu, Sumei
Peng, Jingbo
Yu, Jing
Wu, Huilan
Wu, Wei
Huang, Zhichun
Pan, Jie
Tan, Zhirong
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
National Natural Science Foundation of China (81974510)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Key Project Funded by Hunan Provincial Health Commission (A202313018918)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
Natural Science Foundation of Hunan Province (2021JJ30905, 2022JJ30951, 2024JJ7630)
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Article History
Received: 12 November 2025
Accepted: 6 April 2026
First Online: 15 April 2026
Declarations
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: The authors declare no competing interests.
: The experiments involving patient were approved by the Ethics Committee of the Institute of Clinical Pharmacology of Central South University (Registration no. CTXY-150001-2). Clinical research registration was approved by the Chinese Clinical Trial Registry (Registration no. ChiCTR-DCD-15006289). All patients signed an informed consent form. And the animal experiments were carried out at the Experimental Animal Center of Central South University and approved by the Experimental Animal Ethics Review Committee (No. 2019040625).
