Crossmark

HIF-2α induces aggravated intervertebral disc degeneration by activating the IL-6/hepcidin-FPN1 axis and promoting ferroptosis in nucleus pulposus cells

Crossref DOI link: https://doi.org/10.1038/s41598-026-51095-9

Published Online: 2026-06-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

He, Li-Ming

Gao, Jian

Chang, Qiang

Ma, Zhuo

Guan, Xiao-Ming

Liu, Wen-Bo

Gao, Zhen-Wu

Xi, Lei-Min

Zhou, Yue

Feng, Hao-Yu
Funding

Funding for this research was provided by:

the Fundamental Research Program of Shanxi Province
License Information

Text and Data Mining valid from 2026-06-17

Accepted Manuscript valid from 2026-06-17
More Information

Article History

Received: 8 September 2025

Accepted: 25 April 2026

First Online: 17 June 2026

Declarations

:

: The authors declare no competing interests.

Document is current

Any future updates will be listed below