Harmes, Johannes Christian https://orcid.org/0009-0003-1984-2216
Holtkamp, Mathias
Straus, Jannis
Jost, Gregor
Forsting, Michael
Hosch, René
Nensa, Felix
Pietsch, Hubertus
Salhöfer, Luca
Haubold, Johannes
Funding for this research was provided by:
Universitätsklinikum Essen
Article History
Received: 4 March 2026
Accepted: 22 May 2026
First Online: 28 May 2026
Declarations
:
: The study was performed in cooperation with the Bayer AG. H.P. and G.J. are employees of the Bayer AG. Funding: J.C.H received financial support by the Junior Clinician Scientist Academy of the Medical Faculty of the University of Duisburg-Essen (D/401-90063). L.S. and M.H. received financial support by a German Research Foundation funded Clinician Scientist Academy (FU356/12–2). The funding institutions did not influence the study design, data collection, data interpretation, data analysis, or report writing. The other authors declare that they have not received any funding for this project.
: The manuscript does not contain clinical studies or patient data. The study was approved by the State Animal Welfare Committee (Landesamt für Gesundheit und Soziales, Berlin, Germany), carried out in compliance with the German Animal Welfare Act and under consideration of the ARRIVE guidelines.