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Bioinformatics analysis identifies a novel 4-gene signature associated with immune cell infiltration in osteoarthritis: a combined bioinformatics and experimental validation study

Crossref DOI link: https://doi.org/10.1038/s41598-026-61282-3

Published Online: 2026-07-14

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lu, Lin

Huang, ChengLong

Liu, Pan

Pang, Yi Lin

Huang, ZhaoYang https://orcid.org/0009-0002-0653-4962
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82302026)
License Information

Text and Data Mining valid from 2026-07-14

Accepted Manuscript valid from 2026-07-14
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Article History

Received: 13 January 2026

Accepted: 3 July 2026

First Online: 14 July 2026

Declarations

Competing interests: The authors declare no competing interests.

Ethical approval and consent to participate: The studies involving human participants were reviewed and approved by the Ethics Committee of Renmin Hospital of Wuhan University (Approval Number: IRB No. WDRY2025-K342) in 2025. The study was conducted in accordance with the Declaration of Helsinki (December 2024 version).

Informed consent: Written informed consent was obtained from all individual participants included in the study.

Congress presentation: This research has not been presented at any congress.

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