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Clonal sharing of antimicrobial-resistant bacterial clones and homogenization of the microbiome in the oral, nasal, and endotracheal sites of intubated ICU patients

Crossref DOI link: https://doi.org/10.1038/s41598-026-71025-z

Published Online: 2026-09-22

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yasutomi, Yoshimasa

Nishihama, Saki

Kawayanagi, Tomoki

Asakawa, Mikari

Nishi, Hiromi

Kawada-Matsuo, Miki https://orcid.org/0000-0001-5593-5063
Hisatsune, Junzo

Sugawara, Yo

Shiba, Hideki

Kawaguchi, Hiroyuki

Shime, Nobuaki

Takeshita, Toru

Sugai, Motoyuki

Komatsuzawa, Hitoshi
Funding

Funding for this research was provided by:

JST SPRING (JPMJSP2132)

Medical Research and Development (JP23fk0108606)
License Information

Text and Data Mining valid from 2026-09-22

Accepted Manuscript valid from 2026-09-22
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Article History

Received: 10 April 2026

Accepted: 7 September 2026

First Online: 22 September 2026

Declarations

Competing interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Hitoshi Komatsuzawa reports financial support was provided by The Japan Agency for Medical Research and Development (AMED). If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Ethical approval: All experiments were approved by the Ethics Committee of Hiroshima University Hospital (approval no. E2021-2525). All methods were performed in accordance with approved guidelines and regulations.

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