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Authors
Hua, Ye https://orcid.org/0009-0007-6201-9822
Fu, Siyi
Yin, Lingxuan
Zhang, Yuwei https://orcid.org/0000-0003-1337-1081
Gu, Kaiyuan
Lu, Feng
Xuª, Jia
Zhou, Yuhua
Miao, Huikai
Gu, Jiayu
Sun, Yifan
Chen, Yao
Fan, Yi https://orcid.org/0000-0003-1783-3220
Feng, Ninghan https://orcid.org/0009-0006-7425-8751
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Funding
Funding for this research was provided by:
Wuxi City Science and Technology Innovation and Entrepreneurship Fund "Taihu Light" Science and Technology Research Program (Y20242111)
Scientific Research Project of Jiangsu Provincial Health Commission (M2025017)
National Natural Science Foundation of China (82370777)
Major scientific research Project of the Health Commission of Jiangsu Province (ZD2021002)
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Article History
Received: 17 June 2026
Accepted: 16 September 2026
First Online: 22 September 2026
Declarations
Competing interests: The authors declare no competing interests.
Consent for publication: The content of this manuscript has not been published elsewhere. All authors have reviewed and approved the manuscript for submission. This study does not involve any identifying images, personal or clinical details of participants that would compromise anonymity.
Ethical approval: The study was approved by the Jiangnan University Medical Center Ethics Committee (2024 Y 26) and registered (ISRCTN11583354). All participants provided written informed consent prior to study enrollment. All procedures involving human participants were performed in accordance with the principles of the Declaration of Helsinki.
Informed consent: The studies involving humans were approved by the Jiangnan University Medical Center Ethics Committee (2024 Y 26), and all research procedures involving human participants were strictly conducted in accordance with the principles of the Declaration of Helsinki. Written informed consent was obtained from all participants prior to any study-related procedures.
