Dirner, Anna https://orcid.org/0000-0002-8032-7104
Kormos, Dóra
Lakatos, Dóra https://orcid.org/0000-0002-6461-5800
Bolyácz, Márton
Kocsis-Steinbach, Mária
Kalmár, Gábor György
Tihanyi, Dóra https://orcid.org/0000-0003-0213-7273
Takács, Ákos
Boldizsár, Ákos https://orcid.org/0000-0002-0729-9944
Kardos, Viktor
Szalkai-Dénes, Réka
Vodicska, Barbara https://orcid.org/0000-0003-1191-234X
Várkondi, Edit
Déri, Júlia
Pajkos, Gábor
Mathiász, Dóra
Vályi-Nagy, István
Schwáb, Richárd
Kamal, Maud
Rolfo, Christian https://orcid.org/0000-0002-7860-8417
Dudek, Arkadiusz Z. https://orcid.org/0000-0002-9114-8945
Le Tourneau, Christophe https://orcid.org/0000-0001-9772-4686
Dóczi, Róbert https://orcid.org/0000-0001-5305-8036
Urbán, László
Peták, István https://orcid.org/0000-0003-0422-9286
Funding for this research was provided by:
Nemzeti Kutatási Fejlesztési és Innovációs Hivatal (2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367, 2019-1.1.1- PIACI-KFI-2019-00367)
Article History
Received: 28 November 2024
Accepted: 12 May 2025
First Online: 30 May 2025
Competing interests
: A.D. employment Genomate Health, stock options Genomate Health, D.L. employment Genomate Health, stock options Genomate Health, M.B. employment Genomate Health, M.K.S. employment Genomate Health, stock options Genomate Health, G.G.K. employment Genomate Health, D.T. employment Genomate Health, stock options Genomate Health, A.T. employment Genomate Health, A.B. employment Oncompass Medicine, R.S.D. employment Genomate Health, stock options Genomate Health, B.V. employment Genomate Health, stock options Genomate Health, E.V. employment Oncompass Medicine, J.D. employment Oncompass Medicine, G.P. employment Oncompass Medicine, D.M. employment Genomate Health, R.S. board member Oncompass Medicine and Genomate Health, has research or advisory contracts with G.E., Janssen (Johnson & Johnson), Danone/Nutricia, Novartis, Sanofi, Biogaia Winclove, ProGastro, and Nestle, M.K. had consulting roles with AZD and Roche, C.R. is an advisory board member at AstraZeneca, Daiichi Sankyo, Regeneron and Novocure, Bristol-Myers Squibb (BMS), Novartis, Invitae, Guardant Health, COR2ED, Bayer, Boehringer Ingelheim, Abbvie, Invitae, Janssen, EMD Serono; has research grants from Astra Zeneca, Thermo Fisher, Oncohost, Lung Cancer Research Foundation, National Foundation for Cancer Research, and U54 (National Institute of Health), has research collaborations with GuardantHealth, Foundation Medicine, Roche Diagnostics, EMD Serono; is a scientific advisory board member of Imagene. C.L.T. participated in advisory boards from MSD, BMS, Merck, Astra Zeneca, Celgene, Seattle Genetics, Roche, Novartis, Rakuten, Nanobiotix, and GSK R.D. employment Genomate Health, stock options Genomate Health, I.P. is an employee and equity holder in Oncompass Medicine Inc., and Genomate Health Inc. D.K., V.K., I.V.N., A.Z.D., L.U. These authors declare no competing interests.
: All patients provided written informed consent to use anonymized data for research purposes. Prior to conducting the study, ethics approval was obtained from the National Institute of Pharmacy and Nutrition (approval no. OGYEI/50268/2017), in accordance with the principles of the Declaration of Helsinki.