Xia, Peiyi
Yang, Huan
Yu, Pu
Miao, Yu
Tang, Longfei
Wang, Yuqiang
Li, Binghui
Wang, Zeyuan
Jiang, Guozhong
Chen, Kuisheng
Li, Shenglei
Yang, Minglei
Funding for this research was provided by:
the National Natural Science Foundation of China (62402207)
the National Natural Science Foundation of China (82172941)
the National Natural Science Foundation of China (32500560)
Henan Province Natural Science Foundation (252300421598)
Article History
Received: 9 June 2025
Accepted: 2 March 2026
First Online: 14 March 2026
Competing interests
: The First Affiliated Hospital of Zhengzhou University has filed a pending patent application related to this work (Application Number: 202511022293.8; Status: Substantive examination stage; Filed: September 26, 2025; Title: “Biological Markers for Predicting Melanoma Response to Immunotherapy and Their Application"; Applicant: The First Affiliated Hospital of Zhengzhou University; Inventors: Minglei Yang, Peiyi Xia; Coverage: Use of CD27 as a predictive biomarker for melanoma immunotherapy response). The other authors declare no competing financial or non-financial interests.