Lauffenburger, Julie C. http://orcid.org/0000-0002-4940-4140
Yom-Tov, Elad
Keller, Punam A.
McDonnell, Marie E.
Crum, Katherine L. http://orcid.org/0000-0002-0074-0645
Bhatkhande, Gauri
Sears, Ellen S.
Hanken, Kaitlin
Bessette, Lily G. http://orcid.org/0000-0003-1088-8579
Fontanet, Constance P.
Haff, Nancy
Vine, Seanna
Choudhry, Niteesh K.
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute on Aging (P30AG064199, P30AG064199)
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (K01HL141538)
U.S. Department of Health & Human Services | NIH | National Institute on Aging
Article History
Received: 1 August 2023
Accepted: 5 February 2024
First Online: 19 February 2024
Competing interests
: At the time this study was conducted, E.Y.-T. was an employee of Microsoft. N.K.C. serves as a consultant to Veracity Healthcare Analytics and holds equity in RxAnte and DecipherHealth; unrelated to the current work, N.K.C. has also received unrestricted grant funding payable to Brigham and Women’s Hospital from Humana. N.H. has received personal fees from Cerebral unrelated to the current work. The remainder of the authors report no conflicts of interest.
: The trial was approved by the institutional review board (IRB) of Mass General Brigham and registered with clinicaltrials.gov (NCT04473326). The authors were responsible for performing study analyses, writing the manuscript, substantive edits, and submitting final contents for publication. Patients were not blinded due to the nature of the interventions. No data monitoring committee was deemed necessary by the IRB.