Lee, Ho-Joon http://orcid.org/0000-0003-3616-5387
Schwamm, Lee H. http://orcid.org/0000-0003-0592-9145
Sansing, Lauren H.
Kamel, Hooman
de Havenon, Adam
Turner, Ashby C.
Sheth, Kevin N. http://orcid.org/0000-0003-2003-5473
Krishnaswamy, Smita http://orcid.org/0000-0001-5823-1985
Brandt, Cynthia
Zhao, Hongyu http://orcid.org/0000-0003-1195-9607
Krumholz, Harlan http://orcid.org/0000-0003-2046-127X
Sharma, Richa http://orcid.org/0000-0003-0798-2353
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (K23NS121634, U24NS107243, R01NS111952, R21NS108060, R01NS095993, R01NS097728, U01NS106513, R01NS11072, R01NR018335, R01EB301114, R01MD016178, R03NS112859, U24NS107215, U24HG012108)
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
The Risk Management Foundation of the Harvard Medical Institutions, Inc.
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (R01HL144541)
Received investigator‐initiated clinical research funding from the American Academy of Neurology
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R01GM130847, R01HD100035, R01NS100547)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences
U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke
Article History
Received: 2 October 2023
Accepted: 23 April 2024
First Online: 17 May 2024
Competing interests
: H.L., L.H.S., and R.S. are co-inventors of U.S. Provisional Patent Application No. 63/505,006, “Methods of Training an Algorithm To Predict Ischemic Stroke Etiology”. H.L. reports a consulting role at Guidepoint outside of this submitted work. H.M.K. works under contract with the Centers for Medicare & Medicaid Services to support quality measurement programs, was a recipient of a research grant from Johnson & Johnson, through Yale University, to support clinical trial data sharing; was a recipient of a research agreement, through Yale University, from the Shenzhen Center for Health Information for work to advance intelligent disease prevention and health promotion; collaborates with the National Center for Cardiovascular Diseases in Beijing; receives payment from the Arnold & Porter Law Firm for work related to the Sanofi clopidogrel litigation, from the Martin Baughman Law Firm for work related to the Cook Celect IVC filter litigation, and from the Siegfried and Jensen Law Firm for work related to Vioxx litigation; chairs a Cardiac Scientific Advisory Board for UnitedHealth; was a member of the IBM Watson Health Life Sciences Board; is a member of the Advisory Board for Element Science, the Advisory Board for Facebook, and the Physician Advisory Board for Aetna; and is the co-founder of Hugo Health, a personal health information platform, and co-founder of Refactor Health, a healthcare AI-augmented data management company. A.D.H. has received consultant fees from Integra and Novo Nordisk, has equity in TitinKM and Certus, and receives author fees from <i>UpToDate</i>. K.N.S. reports investigator‐initiated clinical research funding to Yale from Hyperfine, Inc., Biogen, and Bard; reports from Sense and Zoll for data and safety monitoring services; compensation from Cerevasc for consultant services; compensation from Rhaeos for consultant services, compensation from Certus for consultant services; and a patent pending for Stroke wearables licensed to Alva Health. S.K. is on the scientific advisory board of KovaDx and AI Therapeutics. H.K. reports compensation from Novo Nordisk for end-point review committee services, compensation from Medtronic for other services, compensation from Janssen Biotech for other services, compensation from Boehringer Ingelheim for end-point review committee services, and employment by Weill Cornell Medical College. L.H.S. reports compensation as a scientific consultant regarding trial design and conduct on late window thrombolysis and member of steering committee for Genentech (TIMELESS NCT03785678); user interface design and usability to LifeImage (privately held teleradiology company); member of a Data Safety Monitoring Board (DSMB) for Penumbra (MIND NCT03342664; PI, multicenter trial of stroke prevention in atrial fibrillation for Medtronic (Stroke AF NCT02700945). The remaining authors declare no competing interests.