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Article History

Received: 3 June 2024

Accepted: 29 April 2025

First Online: 10 May 2025

Competing interests

: C.M.W. has active research grants to the University for digital health projects from the DIZH, the Swiss Cancer Research foundation, the German health care Innovation Fund, and Newsense Lab GmbH and has received honoraria from Swiss hospitals for scientific presentations on the digitalization and AI in medicine. F.S. is founder of Byldr, which is company for developing mobile health solutions. During the development of CanRelax 2, T.K., F.S., and P.S. were developers and promoters of the open-source software platform MobileCoach. T.K. and P.S. are affiliated with the Centre for Digital Health Interventions (CDHI), a joint initiative of the Institute for Implementation Science in Health Care, University of Zurich, the Department of Management, Technology, and Economics at ETH Zurich, and the Institute of Technology Management and School of Medicine at the University of St.Gallen. C.D.H.I. is funded in part by CSS, a Swiss health insurer, MTIP, a Swiss digital health investor company, and Mavie Next, an Austrian health provider. T.K. was also a co-founder of Pathmate Technologies, a University spin-off company that creates and delivers digital clinical pathways. However, Pathmate Technologies, CSS, MTIP, and Mavie Next were not involved in this research. J.B. received honoraria for workshops on digital health. M.E. received institutional research grants from Kaiku Health and reports grants from Bristol Myers Squibb, Roche and institutional fees as a Scientific Advisory Board Member/Consultant from Roche, outside the submitted work. The remaining authors have no conflicts of interest to declare.