Cai, Dewen https://orcid.org/0009-0001-2406-3597
Kawano, Fuun
Otabe, Takahiro https://orcid.org/0000-0001-7029-1913
Hashimoto, Koji https://orcid.org/0000-0001-8024-0060
Sato, Moritoshi https://orcid.org/0000-0002-3095-5831
Funding for this research was provided by:
MEXT | JST | Precursory Research for Embryonic Science and Technology (JPMJPR1783)
MEXT | Japan Society for the Promotion of Science (19K23716)
MEXT | Japan Society for the Promotion of Science (20K15394)
MEXT | Japan Society for the Promotion of Science (22K05311)
MEXT | Japan Society for the Promotion of Science (22K18338)
MEXT | Japan Society for the Promotion of Science (25H00909)
MEXT | JST | Core Research for Evolutional Science and Technology (JPMJCR23B4)
Japan Agency for Medical Research and Development (25bm1123018h0003)
Mochida Memorial Foundation for Medical and Pharmaceutical Research (not applicable)
Takeda Science Foundation (not applicable)
Naito Foundation (not applicable)
Article History
Received: 14 January 2022
Accepted: 2 December 2025
First Online: 14 December 2025
Competing interests
: The authors declare no competing interests.