Huang, Qiyun https://orcid.org/0000-0003-0570-4771
Chen, Di
Pereira, Andreia C.
Leonard, Alison
Ellis, Claire L. https://orcid.org/0000-0002-1064-2395
Velthuis, Hester
Dimitrov, Mihail https://orcid.org/0000-0002-0760-5905
Ponteduro, Francesca M.
Wong, Nichol M. L. https://orcid.org/0000-0003-0050-7736
Kowalewski, Lukasz
Pretzsch, Charlotte M. https://orcid.org/0000-0002-2761-6628
Daly, Eileen https://orcid.org/0000-0003-3625-3467
Murphy, Declan G. M. https://orcid.org/0000-0002-6664-7451
McAlonan, GrĂ¡inne M. https://orcid.org/0000-0002-4466-2343
Funding for this research was provided by:
National Natural Science Foundation of China (2024A1515011690)
Article History
Received: 25 June 2025
Accepted: 9 January 2026
First Online: 24 January 2026
Competing interests
: The authors acknowledge that this investigator-initiated study was part-funded by Clinical Research Associates, a subsidiary of the Simons Foundation. This included the donation of arbaclofen. The funders did not influence the study design, its conduct or decision to publish outcomes. No other competing interests are declared.