Crossmark

NRF2 activators and the inhibitor of nuclear export, selinexor, restrict coronaviruses by targeting a network involving ACE2, TMPRSS2, and XPO1 through an NRF2-independent mechanism

Crossref DOI link: https://doi.org/10.1038/s42003-026-09724-6

Published Online: 2026-02-20

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Waqas, Fakhar H.

Silva da Costa, Leandro https://orcid.org/0000-0001-9697-4894
Zapatero-Belinchón, Francisco J. https://orcid.org/0000-0002-2751-8411
Carter-Timofte, Madalina E.

Lasswitz, Lisa

van der Horst, Demi

Möller, Rebecca

Dahlmann, Julia

Olmer, Ruth

Geffers, Robert

Gerold, Gisa

Olagnier, David https://orcid.org/0000-0001-6912-0674
Pessler, Frank https://orcid.org/0000-0002-3434-2311
Funding

Funding for this research was provided by:

Bundesministerium für Bildung und Forschung (01KI20143C)

Deutsche Forschungsgemeinschaft (158989968)

Novo Nordisk Foundation Center for Basic Metabolic Research (NNF22OC0079512)
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Text and Data Mining valid from 2026-02-20

Version of Record valid from 2026-03-16
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Article History

Received: 14 April 2025

Accepted: 6 February 2026

First Online: 20 February 2026

Competing interests

: The authors declare no competing interests.

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