Prasad, Gino https://orcid.org/0000-0003-4590-1278
Rajkumar, Utkrisht
Curtis, Ellis J.
Wong, Ivy Tsz-Lo https://orcid.org/0000-0002-9761-3422
Yan, Xiaowei https://orcid.org/0000-0002-4846-8812
Zhang, Shu
Brückner, Lotte https://orcid.org/0000-0002-6155-2277
Turner, Kristen
Wiese, Julie
Wahl, Justin
Hemmati, Homa
Wu, Sihan https://orcid.org/0000-0001-8329-7492
Theissen, Jessica
Fischer, Matthias https://orcid.org/0000-0003-1363-1242
Chang, Howard Y. https://orcid.org/0000-0002-9459-4393
Henssen, Anton G. https://orcid.org/0000-0003-1534-778X
Mischel, Paul S. https://orcid.org/0000-0002-4560-2211
Bafna, Vineet https://orcid.org/0000-0002-5810-6241
Funding for this research was provided by:
Cancer Research UK (CGCATF-2021/100012+ CGCATF-2021/100025)
National Science Foundation (DGE-2545911)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (U24CA264379)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R01GM114362)
U.S. Department of Health and Human Services (OT 140D042590013)
Damon Runyon Cancer Research Foundation (DRG-2474-22)
Article History
Received: 17 June 2025
Accepted: 24 March 2026
First Online: 11 April 2026
Competing interests
: V.B. is a cofounder, paid consultant, and SAB member and has equity interest in Boundless Bio and Abterra Biosciences. The terms of this arrangement have been reviewed and approved by the University of California, San Diego, in accordance with its conflict-of interest policies. H.Y.C. is an employee and stockholder of Amgen. H.Y.C. is a cofounder of Accent Therapeutics, Boundless Bio, Cartography Biosciences, and Orbital Therapeutics and was an advisor of 10x Genomics, Arsenal Biosciences, Chroma Medicine, and Spring Discovery. P.S.M. is a cofounder and advisor of Boundless Bio. S. Wu is a member of the scientific advisory board of Dimension Genomics Inc. The remaining authors declare no competing interests.