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CRYAB_K92 lactylation drives hypertrophy of the ligamentum flavum via an S100A16/RAGE-mediated glycolysis-fibrosis positive feedback loop

Crossref DOI link: https://doi.org/10.1038/s42003-026-10103-4

Published Online: 2026-05-08

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Li, Jianjun https://orcid.org/0000-0002-8928-3523
Yu, Cheng https://orcid.org/0009-0000-2716-5997
Cheng, Junjie https://orcid.org/0009-0000-2520-6054
Cao, Yanlin https://orcid.org/0000-0003-0714-6064
Lin, Tao https://orcid.org/0000-0003-1315-2444
Ni, Songjia https://orcid.org/0000-0003-0475-1226
Hu, Konghe https://orcid.org/0000-0002-3090-6095
Duan, Yang https://orcid.org/0000-0003-4809-9516
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Text and Data Mining valid from 2026-05-08

Accepted Manuscript valid from 2026-05-08
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Article History

Received: 29 July 2025

Accepted: 10 April 2026

First Online: 8 May 2026

Competing interests

: The authors declare no competing interests.

: We have obtained consent signed by the participants to publish.