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Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead

Crossref DOI link: https://doi.org/10.1038/s42004-024-01388-9

Published Online: 2024-12-19

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Mathiesen, Isabel R. https://orcid.org/0000-0003-1854-405X
Calder, Ewen D. D. https://orcid.org/0000-0001-7201-8451
Kunzelmann, Simone https://orcid.org/0000-0002-2678-0549
Walport, Louise J. https://orcid.org/0000-0002-3795-8365
Funding

Funding for this research was provided by:

Cancer Research UK (CC2030)

Wellcome Trust (CC2030)

RCUK | Engineering and Physical Sciences Research Council (EP/X020878/1)

RCUK | Medical Research Council (CC2030)
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Text and Data Mining valid from 2024-12-19

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Article History

Received: 31 July 2024

Accepted: 4 December 2024

First Online: 19 December 2024

Competing interests

: The authors declare no competing interests.

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