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Authors
Kao, Kerry Y. https://orcid.org/0000-0001-7095-4836
Childers, Matthew Carter https://orcid.org/0000-0003-2440-9612
Pathak, Divya https://orcid.org/0000-0001-9944-2308
Goluguri, Rama Reddy
McMillen, Timothy S.
Powers, Joseph D.
Ruppel, Kathleen M.
Spudich, James A. https://orcid.org/0000-0002-4324-4254
Regnier, Michael https://orcid.org/0000-0001-5437-9851
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Article History
Received: 27 September 2025
Accepted: 17 April 2026
First Online: 5 May 2026
Competing interests
: M.R. is a consultant for Kardigan Bio and Bristol Myers Squibb; serves on the scientific advisory board for FilamenTech; and has equity in StemCardia, Inc and KineaBio, Inc; none of the current work is in conflict with these associations. J.A.S. is cofounder and on the Scientific Advisory Board of Cytokinetics, Inc., a company developing small molecule therapeutics for treatment of hypertrophic cardiomyopathy, but this work was done independently. J.A.S. is cofounder and Executive Chair, and K.M.R. is cofounder and Research and Clinical Advisor, of Kainomyx, Inc., a company developing small molecule therapeutics targeting cytoskeletal proteins for multiple diseases, but this work was done independently. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
