Lockhart, Sam M. https://orcid.org/0000-0003-2092-4350
Muso, Milan https://orcid.org/0009-0004-4268-1817
Zvetkova, Ilona
Lam, Brian Y. H. https://orcid.org/0000-0002-3638-9025
Ferrari, Alessandra
Schoenmakers, Erik https://orcid.org/0000-0003-0674-8282
Duckett, Katie
Leslie, Jack https://orcid.org/0000-0001-6443-2396
Collins, Amy https://orcid.org/0000-0003-3619-2588
Romartínez-Alonso, Beatriz https://orcid.org/0000-0002-3061-6696
Tadross, John A. https://orcid.org/0000-0002-8424-1252
Jia, Raina
Gardner, Eugene J. https://orcid.org/0000-0001-9671-1533
Kentistou, Katherine https://orcid.org/0000-0002-5816-664X
Zhao, Yajie https://orcid.org/0000-0002-2747-0219
Day, Felix https://orcid.org/0000-0003-3789-7651
Mörseburg, Alexander
Rainbow, Kara
Rimmington, Debra
Mastantuoni, Matteo
Harrison, James https://orcid.org/0000-0003-4960-5062
Nus, Meritxell https://orcid.org/0000-0002-6378-8910
Guma’a, Khalid https://orcid.org/0009-0000-3835-6115
Sherratt-Mayhew, Sam https://orcid.org/0009-0001-6197-3645
Jiang, Xiao
Smith, Katherine R.
Paul, Dirk S. https://orcid.org/0000-0002-8230-0116
Jenkins, Benjamin https://orcid.org/0000-0003-0038-9709
Koulman, Albert https://orcid.org/0000-0001-9998-051X
Pietzner, Maik https://orcid.org/0000-0003-3437-9963
Langenberg, Claudia https://orcid.org/0000-0002-5017-7344
Wareham, Nicholas https://orcid.org/0000-0003-1422-2993
Yeo, Giles S. https://orcid.org/0000-0001-8823-3615
Chatterjee, Krishna
Schwabe, John https://orcid.org/0000-0003-2865-4383
Oakley, Fiona https://orcid.org/0000-0001-8692-1836
Mann, Derek A. https://orcid.org/0000-0003-0950-243X
Tontonoz, Peter https://orcid.org/0000-0003-1259-0477
Coll, Anthony P.
Ong, Ken
Perry, John R. B. https://orcid.org/0000-0001-6483-3771
O’Rahilly, Stephen https://orcid.org/0000-0003-2199-4449
Funding for this research was provided by:
Wellcome Trust (WT 095515/Z/11/Z, WT 225479/Z/22)
Article History
Received: 17 May 2024
Accepted: 5 August 2024
First Online: 25 September 2024
Competing interests
: S.O. has undertaken remunerated consultancy work for Pfizer, Marea Therapeutics, Third Rock Ventures, AstraZeneca, NorthSea Therapeutics and Courage Therapeutics. S.L. participates in paid consultancy for Eolas Medical. E.J.G. and J.R.B.P. are employees of Insmed Innovation UK and holds stock/stock options in Insmed. J.R.B.P. performs paid consultancy for WW International and receives research funding from GSK. Y.Z. is a UK University Worker of GSK. X.J., K.R.S. and D.S.P. are current employees and/or stockholders of AstraZeneca. D.A.M. & F.O. are directors and employees and directors of Fibrofind Limited. D.A.M., J.L. and F.O. are shareholders in Fibrofind IP and Fibrofind Limited. The other authors declare no competing interests. For the purpose of open access, the authors have applied a creative commons attribution (CC BY) licence to any author-accepted manuscript arising from this submission.